Applications are invited for a postdoctoral Research Associate to start as soon as possible to work with Professor Richard Durbin in the Department of Genetics on studies into the contribution of different ancient human ancestries to present day disease risk. Professor Durbin is involved in major studies into ancient human genome DNA sequencing and analysis from across Europe, in collaboration with Professor Eske Willerslev from the Department of Zoology and others. The research associate will use data from these studies to trace haplotypes from the UK Biobank back in time to specific ancient populations, and assess the contribution of these ancestries to genetic risk for modern polygenic phenotypes. Applicants should be able to demonstrate significant experience in processing very large amounts of whole genome genotype data, and in the analysis of ancient DNA data. They must have good general computing skills with Python and statistical genetics expertise, in particular in the generation and use of polygenic risk scores and in local ancestry inference. Specific prior experience with BioBank data would be very desirable.
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